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whats up with that 

One of the funniest series of sketches Saturday Night Live have ever made.
Seriously search "Whats up with that snl" on Youtube
Kenan Thompson "Ooooh yeah, Whats up up with that, whats up with that"

That's whats up 

Used to agree with something, To say you like something, When you don't know what else to say, and when you don't know how to answer a text.
-I'll be there later.
-That's whats up.

-So, I'm bored.
-That's whats up.

-Wanna get burritos?
-That's whats up!!
That's whats up by I'mwhatsup(: February 11, 2010

Whats up with that 

Something that is non uderstandable
you see a rich guy in a toyota
"whats up with that"

that's whats up good lookin out 

1. an expression of approval and thanks for a good deed, OR, 2. can be used in sarcasm to show disinterest in someone's actions or feelings
1. Miss Utility: "I'm not wearing any panties."
Tito: "That's whats up good lookin out!"
or
Danny: "I got laid off today. I need to look for a new job."
Tito: "That's whats up good lookin out?

That's whats witted!!! 

That is smart or that is a good idea!!!
You at the shoe store about to by one pair of J's but they got a sell for buy one get one half off. So, your homie tells you to take the sell. You respond by saying "That's whats witted!!! Good lookin."

please note this does not account for all members of the minorities listed above,as in meaning not all black/white/black-wannabe's are like that,but to be fully truthfull alot are,and thats whats wrong with our world nowadays.. 

A really shitty use of the word tag
If you clicked this, you know