Tweaking

1. To be under the effects of amphetamines, esp. crystal methamphetamine hydrochloride.

2. To be nervous or worried about something, esp. the presence of law-enforcement personnel.

1. Dude I took a fat hit of some dank ice and I'm tweaking balls!

2. Dude I got pulled over with an o in my glove compartment and I was tweaking balls!

by Bri90 January 28, 2010

Tweaking

Someone who is really high on ice or meth!!!

Damn that dude is tweaking balls!

by Realfunni February 24, 2019

Tweaking

To freak out while intoxicated.

“Omg she’s tweaking, she must be hallucinating.”

by Vatrinna March 16, 2021

Tweaking

Obsessive repetitive behavior

Look at him hes tweaking out!

by Slim kitty February 7, 2017

Tweaking

To do crack or act like doing crack/cocaine.

Most of the time used in a question

"Gave who some dam money? I aint gave no nobody no damn money girl! IS YOU TWEAKING!?" By R-kelly Real Talk

by HondaKiller2TGR June 18, 2008

Tweaking

A crack head in withdrawal after being denied a dollar from a stranger

That white boy over there tweaking because I wouldn’t give him a dollar

by jmusic January 29, 2020

Tweaking

Starting unnecessary problems or arguments. Usually about a certain action of yours or as a response to something you said. Or even about something unrelated to you.

“Hey, so you still down to go out tonight?” Molly
“Dang, hold on. My girlfriend just started tweaking about how the living room is a mess.”

by Batman in 2006 August 20, 2021