People who are paranoid, delusional, uneducated, and covered with oozing chemical scabs and ulcers due to the acute abuse of methamphetamine. They eventually eat scabs from one another that contain the meth that their body can't dispose of, just to catch a cheap thrill. MMMMM....MMMMMMMMM!!!
by running out of patience January 6, 2008

A person that is under the influence of methamphetamines and is in the middle of three projects at the same time none of which will ever be completed.
I watched Johnny search through his bag with one hand while making something with the other,he is such a tweaker.
by Jamie Pheloney April 9, 2005

A person who does Crystal Meth. They talk very fast all the time. You're lucky to get a word in with a serious tweaker. They do obsessive projects ranging from, taking a TV set apart, to cleaning a tile floor with a tooth brush. Not finishing anything is common. The thing about meth is that some people have done so much, that even when they quit, they are so damaged that they retain all the characteristics of a tweaker. Ruined for life.
by Roadie Overthegate March 11, 2007

by Yramesor! April 14, 2004

Some one who does crystal aka tweak and has been up for days showing signs by talkng alot pacing around and fidgiting
by Lisa April 9, 2004

A person that can't stay still and is constantly occupying themselves with meaningless activities which will never be be completed.
by Jamie Pheloney April 9, 2005

by Rokki J. Rand November 2, 2007
