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1. A common culinary herb, it has an aromatic, warm, and slightly bitter taste. Currently it sees the most use in Italian-American cuisine.

2. A funny way of saying 'Original', usually said in a sarcastic way.
1. Person: This oregano is pretty good on my spaghetti.
2. Person: Great joke, really oregano.
"I don't have any Weed, Jim"
"It doesn't matter, I have some Oregano"

oregano prank 

a random act of douchebaggery; an arbitrary, pointless prank. originated from a myth where a group of tricksters would fill dime bags with scrunched-up oregano to imitate bags of weed, which they left at popular smoking spots. stoners finding the bags would soon cheer their good fortune and then lament their awful fortune upon realizing they had smoked a culinary herb.
douchebag: "mikhail just asked me to get him some coca cola, but i know he hates diet, and since the diet and regular varieties are visually indistinguishable, i will fill his cup with diet coke and watch him react in disgust when he drinks it!"

normal person: "you are such a child. grow up and stop pulling oregano pranks"

Oregano Man 

A connoisseur of all aspects of pizza. Primarily specialized in the differentiations of pizzerias in the general locale. Typically, an Oregano Man has worked with pizza at a young age, possibly at his/her family’s pizzeria.
The Oregano Man has yet to distinguish the difference between Sam's Pizza and Mack's Pizza, but once he does, the results will be epic.

oregano trail 

She took her pants off and had an oregano trail but after I went down on her I came down with dysentery.
oregano trail by abacus-succubus February 28, 2023

Oregon Oregano

The type of weed everyone in Boise smokes.
Hey man, let’s pick up some Oregon Oregano™ this weekend.
Oregon Oregano by Fred Sampson December 11, 2022