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fucked-up 

means to be really messed up usually referring to the head.
Whoa!, that guy is Fucked-up!

fucked up 

Describes action or situation that conflicts with logic or certain expectations.

Note: Often used in place of the word "Wrong" or the phrase "not right". However, the phrase "Fucked up" is unburdened by any idea of absolute rightness or wrongness. Whereas describing an action or situation as wrong in this manner may imply some sort of anomaly in an assumedly perfect universe, a situation described as fucked up can be viewed merely as the product of a Universe that is just fucked up in general.
"That's was wrong."
"2+2=5 is wrong. That was fucked up."

"That's fucked up."
"65 million years ago, an asteroid killed every living thing on this plante bigger than a rat, now THAT was fucked up."
fucked up by Alfred Mordeir December 30, 2006

Fucked up 

A vulgar way of expressing a situation that is unsurmountably ruined or messed up ; often a way of emphasising the stupidity of said person's actions and intended to offend them on a mental level ; an elevated way of describing a pure dumbass
John: I gave Jim 20 quarters and in return I got 100 pennies! What a TRADE! :D
James: Dude you can't get more fucked up than that....
Fucked up by SiddyBoo June 2, 2015

fucked up 

When you drive 8 hours to see your girlfriend and she doesnt wanna drive 2 hours to pick you up
so lauren, you would rather have me not come see you than you drive to pick me up?
"ya thats right"
wow thats fucked up
fucked up by wet metal April 1, 2008

Fucked Up 

1. something that is ignorant, has no purpose, is retarded 2. what happens when you go to a good party
1. "did you see him run into that wall? that was so fucked up!"
2. "man, we were so fucked up last night!"
Fucked Up by RoflicerOfTheLawl January 16, 2008