Best girl syndrome is when someone feverishly believes that their favourite character in fiction (typically a female in anime, hence the name) is the best character and will be stubborn in saying that theirs is the best and everyone should like it, and that if they don't they simply say that they know them better and say that the other person is in denial, not considering the fact that other people have different opinions.
Guy 1: god I love insert anime waifu here
Guy 2: nah is insert different anime waifu is better.
Guy 1: fair enough, I just like mine better.
Guy 2: you don't seem to get it, they are better.
Guy 1: ...to you maybe, but I still prefer anime waifu1.
Guy 2: you just aren't giving them a chance! Stop being stubborn about it!
Guy 1: and you have Best Girl Syndrome
Guy 2: nah is insert different anime waifu is better.
Guy 1: fair enough, I just like mine better.
Guy 2: you don't seem to get it, they are better.
Guy 1: ...to you maybe, but I still prefer anime waifu1.
Guy 2: you just aren't giving them a chance! Stop being stubborn about it!
Guy 1: and you have Best Girl Syndrome
by Undert23 November 8, 2019
Get the Best Girl Syndromemug. People started laughing at the has been sexiest guy/girl.
Guy- You know he/she was the sexiest guy/girl in the late 80s dont you?
Other guy- You know who the sexiest guy/girl was in the 80s? What the fuck are you doing here? Nobody would like that squishy faced, diamond eyed, spaghetti noodled Western retard if they knew who he was.
Guy- I know what you're trying to say dude, I understand your language. I never get any joy from things like this either, there is nothing funny about it, I am with you no matter what, I will always be loyal to you as your friend. I must choose this option, even though I'm not dumb, even though I know there are other options, I still choose this because even though I'm not the only person who doesnt have much self confidence, I still try to fuck with people who are trying by telling them about their arrogance even if they're humble and modest people. I'd rather keep doing that without them or me ever finding out what's really wrong with me. Sometimes I feel so much rougher than other people my age, like they could never have gone through what I went through and make it like I did, or like their thoughts and emotions could never get as deep as mine.
Guy- You know he/she was the sexiest guy/girl in the late 80s dont you?
Other guy- You know who the sexiest guy/girl was in the 80s? What the fuck are you doing here? Nobody would like that squishy faced, diamond eyed, spaghetti noodled Western retard if they knew who he was.
Guy- I know what you're trying to say dude, I understand your language. I never get any joy from things like this either, there is nothing funny about it, I am with you no matter what, I will always be loyal to you as your friend. I must choose this option, even though I'm not dumb, even though I know there are other options, I still choose this because even though I'm not the only person who doesnt have much self confidence, I still try to fuck with people who are trying by telling them about their arrogance even if they're humble and modest people. I'd rather keep doing that without them or me ever finding out what's really wrong with me. Sometimes I feel so much rougher than other people my age, like they could never have gone through what I went through and make it like I did, or like their thoughts and emotions could never get as deep as mine.
by Solid Mantis September 23, 2020
Get the Has been sexiest guy/girlmug. basically the new tumbler girls. it used to be the basic white chicks but that is so 2017. vsco girl's wear airforce ones ,birks ,vans, or crocs. they are dressed in over sized t shirts and wear puka shell necklaces, scrunchies, friendship bracelets, and carry hydroflasks. if ur a vsco girl, u will never EVER EVERRRRR be caught with plastic straws because theyre all about saving the turtles. also they say and i oop- and sksksksksksksksksksksks A LOTTTT
by xoxo vscogirlllll November 6, 2019
Get the vsco girlmug. 
by Vsco and I oop October 21, 2019
Get the Vsco girlmug. Boy 1: I just broke up with Sarah after 6 months dude
Boy 2: Isn’t she a full grown man now?
Boy 1: Yeah she’s such a Colins girl
Boy 2: Isn’t she a full grown man now?
Boy 1: Yeah she’s such a Colins girl
by PogRider7 April 22, 2022
Get the Colins girlmug. by that itch September 8, 2015
Get the annoying facebook girlmug.