by KatLovesBands February 23, 2015
by DUFF HUNTER August 16, 2009
Duff is an acronym meaning Dumb Ugly Fat Friend or Designated Ugly Fat Friend.
Generally a cockblocker and a bitch, have a desperate friend take her down.
Generally a cockblocker and a bitch, have a desperate friend take her down.
Friend 1: Dude I want to hook up with that girl, but her duff is in my way.
Friend 2: It may be Amber but i'll take the duff down.
Friend 2: It may be Amber but i'll take the duff down.
by Jap Anus Relations July 30, 2009
by mobojobo February 02, 2015
a duff is another definition of a noob; a term used when sombody makes a stupid mistake or does something stupid.
Alex: oh my god my ball hairs itch like hell, man.
Morgan: wait, you have hair on your balls.
Alex: wow, your a fucking duff.
Morgan: wait, you have hair on your balls.
Alex: wow, your a fucking duff.
by DJCVans July 01, 2006