A line in the United States between the North and the South where Yankees go to take a shit and Confederates go to eat.
Rebels head north to the Mason-Dixon line for dinner, while the Damyankees slide south to take a crap.
by Bigyank January 11, 2012
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So I was watching COPS, and they pulled over a guy with a joint behind his ear. He had a major case of Mason-Dixon Line Syndrome.
by Dr Shea Foster, DDR December 22, 2008
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