When a girl voluntarily takes sleeping pills before sex and let's you "have at it"! Especially done when losing ones virginity because "the first time can hurt".
Yo I was talking to this girl and she said she wanted the Melatonin Mamba to lose her virginity. I said "no way hombre that's nuts you're still a virgin, I don't want to tear a labia", and she said "just do it you pussy, I don't want it to hurt!"
by brosefballin October 4, 2022
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A group of people who engage in secretive activities; often of the homosexual variety
Bro here comes the mambas we better get out of here so we don't get ass fucked
by Decakaren May 1, 2019
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A mixed drink made from blue Hawaiian Punch and whipped cream vodka.
That blue mamba last night was the best thing I ever drank!
by MangomanG0 July 1, 2017
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A mamba tank is shay off a pack of bears
Shays a fucking mamba tank
by Finn Parkin October 9, 2020
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Having sex with 24 people in 8 days.
Dude 1: my balls hurt from doing the mamba challenge

Dude 2: mamba challenge?

Dude 1: yeah man, f***ing 24 girl in 8 days, you know, for Kobe.
by Uzika February 10, 2020
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