DUFF

Wow, who brought the Duff to the party!?!? Not cool guys...
by DUFF HUNTER August 16, 2009
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Duff

Duff is an acronym meaning Dumb Ugly Fat Friend or Designated Ugly Fat Friend.

Generally a cockblocker and a bitch, have a desperate friend take her down.
Friend 1: Dude I want to hook up with that girl, but her duff is in my way.

Friend 2: It may be Amber but i'll take the duff down.
by Jap Anus Relations July 30, 2009
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Duff

the ugliest friend in a group to make everyone else look better.
by mobojobo February 02, 2015
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duff

faulty, sub-standard
by doof April 23, 2003
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Duff

a duff is another definition of a noob; a term used when sombody makes a stupid mistake or does something stupid.
Alex: oh my god my ball hairs itch like hell, man.
Morgan: wait, you have hair on your balls.
Alex: wow, your a fucking duff.
by DJCVans July 01, 2006
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DUFF

by AshleyHads May 20, 2005
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duff

designated ugly friend.- the girl no guy wants to have.

This girl will usually get ignored when out with her hot friend and may be so ugly the wingman won't even touch her- then the cockblocking comes in.

The ugly friend may suffer from some form of facial deformity such as an outrageously large nose which prevents them from anyone finding them physically attractive.

They usually end up nowhere in life due to their unnatractive looks and may become a stalker so watch out.
wow, her friend is hot but that single mother is a real duff.
by jdjdjd5665 December 04, 2008
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