Up syndrome

you say it to insult someone

you don't have down syndrome you have Up syndrome

by MangoMane January 25, 2025

big head syndrome

when they have a fat dope sack, an think they are a baller, till the sack is alll gone!

as soon as he traded his car for all that dope, HE GOT BIG HEAD SYNDROME an he started barkin orders at people, when its all gone, he will be askin for a handout from me, again

by D4RK5IDE March 4, 2011

Lover Syndrome

When someone avoids you or gives you the cold shoulder due to a significant other, boyfriend, girlfriend, etc. It also implies to people who hang out with their lover and avoid their own friends. (Also referred to as *Simon Syndrome*)

Friend 1: Ugh, ever since Simon started going out with her he's been avoiding all his friends and homies just to spend time with her.

Friend 2: Oh that's definitely *Lover Syndrome*. Guy wants to be around her so much he'll avoid his own friends and ignore them.

by fakepeoplehaterpssstsimon May 11, 2022

MattKC Syndrome

When you become obsessed with modding an obscure childhood game you don't actually play unironically

I'm gonna mod super mario 64! - ok cool!
I'm gonna mod Lego Island! - ..What? this is some mattkc syndrome type shit

by iminhellplshelpahhh May 20, 2025

Hot Boy Syndrome

N; The withdrawal after seeing a hot boy (usually while traveling) and knowing you will almost definitely never see him again

Omg that guy at the rest stop is totally going to give me Hot Boy Syndrome...

by Bitty bae November 11, 2019

Perpetual Pussy Syndrome

Chronic disorder of always being a whiney little bitch. Usually affiiliated with a man possessing effeminate qualities,annoying voice, and a face you just want to punch . Men and women alike distest this individual.

WTF is that guys problem!? All he does is bitch and complain. I just want to punch him in the head! Clearly a case of PPS (perpetual pussy syndrome)

by IncognitoAF June 24, 2017

Wet Snatch Syndrome

The phenomenon of a girl's underwear getting soaking wet after sexual activities or being turned on

Chris: That was great!
Ann: Yeah! But now I've got a case of wet snatch syndrome.

by Little_Annie228 November 19, 2015