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A being of such a massive intellect and high IQ that they are completely unable to function in plebian society.
Oliver is such a god at Smash Bros, I wonder if he has up syndrome.
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by Banana Hammie October 29, 2019
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Apr 20 Word of the Day
A term used to reference cannabis/marijuana/weed.
This Jazz Cabbage got me zooted. Jazz Cabbage is less harmful than Squares. I’m smoking that Jazz Cabbage boy.
by Gypsiehood97 December 30, 2017
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2
Up-Syndrome is when you have more than 62 chromosomes (basically being a SPED Class in one person), this usually occurs in when a male and a female have reproductive sex over the age of 50.
This kid with Up-Syndrome is CRAZY!!!
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by The Up-Syndrome bot April 11, 2019
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6
The condition where genitalia is in a perpetually happy state.
"Tom came down with a case of up-syndrome soon after meeting Caroline."

"We always thought Susie was a bit weird, but we didnt know for certain until her secret reared its ugly little head -- she was diagnosed with up-syndrome."

5:00 News Report:
"Rare condition found in man with up-syndrome... Are two penises better than one?"
by PetShelterPimp March 05, 2005
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