Ethan O’Brien Syndrome

To be a fucking fatass idiot who loves to suck men off

Hey kid, u have Ethan O’Brien Syndrome

by XxxFatacionXxx May 16, 2019

Sam O’Brien

Quadriplegic

Sam O’Brien means
Can’t run for shit but he can hit a ball with a stick

by Fffuiifddtyjbgj May 20, 2019

Aidan O'Brien

Most known for being the JV Lacrosse Captain. He rips Juul all the time(Serious Nicotine Addict). Asked Jade to Prom. Didn't make the Varsity Hockey Team.

Aidan O'Brien, Fat rips only

by Big Bands April 24, 2019

Conan O'Brien

8ft 7" Prepubescent Girl with a face whiter than the typical Republican voter and hair oranger than the cheesiest of cheese puffs. Known for hosting Late Night With Conan O'Brien, before moving on to The Tonight Show with Conan O'Brien, getting screwed by Jay Leno and NBC and then going to TBS with Conan from 2010 until 2021.

Hey, did you watch Conan O'Brien's last show on TBS?
Yeah it was sad :(
Hey, you gonna watch Jay Leno's new TBS show?

by TeamAbzy June 27, 2021

Conan O'Brien

The FUNNIEST man alive.

Late Night With Conan O’Brien Rocks!!!

by Jon March 15, 2005

Conan O'Brien

Host of Late Night with Conan O'Brien. He is planning to take over the Tonight Show in 2009. He is an excellent comedian and is way better than Jay Leno, David Letterman, and Craig Ferguson. Although Ferguson would come in second.

He often uses witty and sarcastic humour to get laughs, and he's great at it.

House band for the show is The Max Weinberg 7.

Announcer is Joel Godard.

Billy: Who's conan o'brien?
Me: a god.

by Jack Townshend June 30, 2006

Brien

Noun; A Giant among men. A Boss. International Player. Savage. Visionary.

Fact: Most children named Brien are extremely talented and 42% have genius IQ's before they have puberty.

"Bruh, props for closing that 6 billion dollar deal! You Brien'd up on that real proper cuhz"

by TheFactsYo February 14, 2017