The act of inserting drugs and/or alcohol into one's rectum to obtain a stronger drunk/high and a quicker onset.
"Brett totally perjured himself when he claimed that boofing actually meant farting, in the context of engaging in benign college hijinks with his buddies, not being repeat offending blackout drunk sexual predators after shoving tubes up each other's asses and pouring beer into them.
"Somehow I reached the ripe old age of 46 before learning about the charming practice called 'boofing' courtesy of Supreme Court Justice Brett Kavanaugh from "The Party of Family Values."
"Somehow I reached the ripe old age of 46 before learning about the charming practice called 'boofing' courtesy of Supreme Court Justice Brett Kavanaugh from "The Party of Family Values."
by Turbokai November 10, 2021

In the 772 it’s used to describe some ass weed or anything ass in general. In the rest of South Florida it’s used to describe some fye shit
772: “I just copped a zip of some zaza from PSL”
“Jhit you bugging that’s some boof shit”
Rest of South Florida: “Just got this new cali pack”
“Oowee that’s that boof!”
“Jhit you bugging that’s some boof shit”
Rest of South Florida: “Just got this new cali pack”
“Oowee that’s that boof!”
by Isuckbecauseimfrom772 September 3, 2020

put it in ya arse
buy a shirt celebrating the boof:
justboofit.printify.me
^ profits go to a single mom
buy a shirt celebrating the boof:
justboofit.printify.me
^ profits go to a single mom
by boof on the roof April 16, 2025

1). (Noun): Slang for marijuana.
2). (Adjective): Something of low quality, very commonly used to describe low quality drugs. It should be noted that the adjective definition is separate from the noun definition, and referring to marijuana as “boof” doesn’t necessarily mean it is low quality.
3). (Verb): To ingest psychoactive drugs rectally. Also known as “booty bumping” or “Plugging.”
Typically the drugs are dissolved in a small amount of water and drawn up into either an oral syringe, or a hypodermic syringe with the sharp taken off (Obviously).
It is VERY important to know that the reason people choose this route of administration is because boofing typically has a MUCH higher bioavailability (The amount that ends up in your bloodstream) than other methods of taking drugs such as orally, smoking, or snorting. It depends on the drug, but boofing is usually a negligible step below injecting as far as how much is absorbed.
For example: Morphine has an oral bioavailability of around 20% and a rectal BA of around 70% (3.5x more), meaning that boofing 10mg of morphine results in the same amount of absorption as 35mg orally which can be a dangerous difference.
Drugs most commonly taken by boofing include MDMA, methamphetamine, cocaine, heroin, fentanyl, and prescription medications. Less common drugs include DMT, LSD, ketamine, and alcohol.
2). (Adjective): Something of low quality, very commonly used to describe low quality drugs. It should be noted that the adjective definition is separate from the noun definition, and referring to marijuana as “boof” doesn’t necessarily mean it is low quality.
3). (Verb): To ingest psychoactive drugs rectally. Also known as “booty bumping” or “Plugging.”
Typically the drugs are dissolved in a small amount of water and drawn up into either an oral syringe, or a hypodermic syringe with the sharp taken off (Obviously).
It is VERY important to know that the reason people choose this route of administration is because boofing typically has a MUCH higher bioavailability (The amount that ends up in your bloodstream) than other methods of taking drugs such as orally, smoking, or snorting. It depends on the drug, but boofing is usually a negligible step below injecting as far as how much is absorbed.
For example: Morphine has an oral bioavailability of around 20% and a rectal BA of around 70% (3.5x more), meaning that boofing 10mg of morphine results in the same amount of absorption as 35mg orally which can be a dangerous difference.
Drugs most commonly taken by boofing include MDMA, methamphetamine, cocaine, heroin, fentanyl, and prescription medications. Less common drugs include DMT, LSD, ketamine, and alcohol.
1). “Just got a pound of the boof, brought that shit straight to the booth.”
-XXXTENTACION on “Look at Me!”
2).
“Yo I bought some shrooms from that guy and they were boof. I ate 3.5 grams and barely tripped.”
3).
Friend 1: “I still have two small lines of coke left, but my nose is plugged and my tolerance is so high I won’t feel it…”
Friend 2: “Boof that shit bro. Trust me it hits like a train.”
Friend 1: “Idk man, doesn’t that make me gay?”
Friend 2: “Fuck no, boofing doesn’t make you gay, but doing coke and binging anime does. Besides there’s nothing wrong with being gay.”
-XXXTENTACION on “Look at Me!”
2).
“Yo I bought some shrooms from that guy and they were boof. I ate 3.5 grams and barely tripped.”
3).
Friend 1: “I still have two small lines of coke left, but my nose is plugged and my tolerance is so high I won’t feel it…”
Friend 2: “Boof that shit bro. Trust me it hits like a train.”
Friend 1: “Idk man, doesn’t that make me gay?”
Friend 2: “Fuck no, boofing doesn’t make you gay, but doing coke and binging anime does. Besides there’s nothing wrong with being gay.”
by danasp_42 October 14, 2023

“That’s boof”
“Yo this song is so boof”
“Yo this song is so boof”
by The Fucking Lizard King December 1, 2020

The act of inserting an object into the anus in order to hide or store it; typically drugs in order to avoid being caught.
Al Capone was said to have boofed many bottles of liquor in order to get those few extra bucks.
She so thicc she could prolly boof a watermelon!
She so thicc she could prolly boof a watermelon!
by Gump II February 14, 2018
