Any man that is a particularly conspicuous alcoholic in comparison to other residents of his hometown. A reference to Otis Campbell who was the town drunk on the Andy Griffith Show as played by Hal Smith.
by lefty lomond September 9, 2018

A medical condition in which certain breeds of Canis familiaris (dogs) exhibit behavioral tendencies often associated with heavy inanimate objects stored in sacks. Common symptoms are lying down at the dog park instead of playing with other dogs, lying down during a walk, and/or lying down during a burglary.
There are no known cures.
There are no known cures.
A: How was your walk with Jerry (basset hound)?
B: Not so great, I had to drag him most of the way.
A: Wow, sounds like Jerry might have lazy-itis-otis. You should really be feeding him a vegan diet.
B: Shut up, Karen.
B: Not so great, I had to drag him most of the way.
A: Wow, sounds like Jerry might have lazy-itis-otis. You should really be feeding him a vegan diet.
B: Shut up, Karen.
by DCA1981 August 5, 2022

OTI, OTI, OTI, OTI!
by badxx July 6, 2023

Person 1: So my mom told me to come home cause she has stuff she needs me to do so I have to go home to do the stuff
Person 2: bro why speakin Otis Speak?
Person 2: bro why speakin Otis Speak?
by Dylde23 October 12, 2021

by Finnking October 16, 2022

by wuakteo. June 9, 2025

A universally disliked piece of footwear. Usually categorized by an entire community’s hatred and outrage regarding it. In some instances loved by nobody.
by Kubby13 September 5, 2019
