Used often in a "No Shit" kinda way, comes from a picture of a snow owl who had a look on his face that the photographer said looked like he was saying "O RLY?"
by Teh Pwnzorhax June 10, 2010

Person 1: Butterflies can talk, and my dog just winked at me
Person 2: what the fuck have you been smoking 0-O
Person 2: what the fuck have you been smoking 0-O
by screw YOU REEEEE August 2, 2019

lead singer of the new york punk band the Yeah Yeah Yeahs. Probably the coolest women on the planet-known for performing weird sexual acts with the microphone when performing live, and dressing up in ridiculous costumes, and drinking loads of booze.
guy 1: hey, did you see karen o at that concert last night
guy 2: No, why?
guy 1: because she got completely wasted and fell off the stage.
guy 2: No, why?
guy 1: because she got completely wasted and fell off the stage.
by admmad March 27, 2008

Abbrevation of orange juice
by zorkA July 10, 2007

Person 1: "Yo what happened to O To The Sev?"
Person 2 "Edot smoked with the opps, that ended their alliance"
Person 2 "Edot smoked with the opps, that ended their alliance"
by Jeviaun August 31, 2023

The only food real dank memesters eat. Especially DANK DORITOS and KINKY FUCKERY WHORES. We run on this shit boii spaghetti O's make the hoes wweeettt
by bootleg_doritos April 8, 2017

by makaveli88 February 21, 2004
