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lead singer of the new york punk band the Yeah Yeah Yeahs. Probably the coolest women on the planet-known for performing weird sexual acts with the microphone when performing live, and dressing up in ridiculous costumes, and drinking loads of booze.
guy 1: hey, did you see karen o at that concert last night
guy 2: No, why?
guy 1: because she got completely wasted and fell off the stage.
by admmad March 27, 2008
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lead singer of the yeah yeah yeahs. an extroverted performer, a good lyricist, and a wearer of crazy stage get-ups. known for swilling beer and spitting it out at the audience.
we need more girls like karen o.
by cock123456789 December 31, 2005
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lead singer of the new york punk band the Yeah Yeah Yeahs. Probably the coolest women on the planet-known for performing weird sexual acts with the microphone when performing live, and dressing up in ridiculous costumes, and drinking loads of booze.
guy 1: hey, did you see karen o at that concert last night
guy 2: No, why?
guy 1: because she got completely wasted and fell off the stage.
by admmad March 27, 2008
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Get a karen o mug for your boyfriend James.