"fo shizzle ma swizzle" is a bastardization of "fo' sheezy mah sweezy" which is a bastardization of "for sure mah sweetie" which is a bastdardization of "I concur with you whole heartedly my sweetheart"
regular dude: "you wanna go eat some food?"
cool lady: "fo' shizzle my swizzle"
Hey make sure that they sanitize that needle when you go in for that industrial piercing... You don't want to catch the Hini Swizzle from a skin stabber... That would be enough to make you really want to mirk-out!!!