S.O 

An acronym for Sexual Orientation.

"Dude, this Natasha girl is hot!"

"Right? RIGHT?"

"By the way, what's her S.O?"

"I hate to break it to you, man, but... I think she's gay."

"Gooooddddaammit! Actually, wait... that's pretty hot."

S.O by Danielakojas February 18, 2019

s.o 

sleep over

hey wanna s.o tonight?

s.o by polandspringthis May 8, 2010

s.o 

s.o- my bith ass survalence office that works for ma p.o so he dont gota get off his fat ass i kant wait to get off so i can get flazed as fuck

s.o - i want yo piss me- then open yo mouth bitch

s.o by gus from tha 520 April 15, 2005

S.o 

Sex offender

"You see that dude right there he showed off his dick to his neighbor now he is a s.o"

S.o by Dope slang July 25, 2018

S.o 

Sex Offender

I did 6 months on a fake S.O charge

Dude over there, he a S.O

S.o by Big Glizzy Bandz March 23, 2019

S.O 

Serhan Official. Gang for dead family members

Keem : Yo what set you claim?
Me: I claim S.O

S.O by s.ogang December 12, 2020

S.O 

Abbreviation for significant other

me and my s.o are going out

S.O by PORCODIOQUELLOVERO January 7, 2022