mdizzle Share definition Flag Slang street term for the drug 3,4-methylenedioxymethamphetamine (MDMA) commonly known as Ecstasy. Phrase was coined in Milton Keynes, England. 'Fancy getting on the mdizzle tonight fella?' mdizzle by mKdave October 16, 2008 0 0 Get merch Get the mdizzle mug. Buy Now — $32.95 See more merch