doofed Share definition Flag To do something in a klutzy, forgetful, aloof, or confused manner. Act as a Doof, fail. I went to the bank to cash my paycheck and realized I hadn't even picked up my check yet. Totally doofed it. doofed by SB85 August 11, 2018 0 0 Get merch Get the doofed mug. Buy Now — $32.95 See more merch