depo 

Depo is an abbreviation of Depressed and can be used in many ways such as:

"That kid alex is sooo depo since he left school"
"I am a depo emo boy"

depo by gorga May 5, 2007

depo 

Depo-Provera. A birth control solution given as a shot. Contains synthesized hormones similar to those in convential birth control pills. Administered as a shot every few months to prevent ovulation.

I asked my girlfriend to start getting depo shots because I didn't want her to get pregnant by my good for nothing sperm.

depo by sMOKEsTACK August 24, 2005

DEPO 

1. Asshole
2. Dumbass
3. Blind to the world.
4. Someone your about to rip off
5. Best Buy slang for a needy customer

Someone who is blind to the world and a jerk at that. Jimmy is a flipping depo!

DEPO by Sketch Agui May 13, 2005

Depo 

Short for Home Depot. Depo is the highest insult to a person's intelligence that one can make, above Hardware store, Toolshed, Toolbox, and Tool.

Bob: Billy still uses Internet Explorer.

Joe: We've always thought he was a Depo, this is just the final nail in his coffin.

Depo by CoonDawg1 March 15, 2009

DEPO 

Dollars expended per orgasm

A unit of measure for compensation in a sugar daddy/sugar baby relationship. His average DEPO with his girl is $500.

DEPO by Random Username 1554 November 11, 2022

Depo 

depressed; sad; untollerable

Aw, poor Mrs.Due, she seems depo!

Depo by Carissa November 23, 2003

depo 

tfc sniper god

depo is a sniper god

depo by 32DePo January 19, 2004