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Formerly used as an onomatopoetic expression to describe the sound of laughter in '60s theatrical jargon.

A decade later was used as an expression of distaste, disgust, or revulsion by people who attended comedy clubs, probably due to the disgusting nature of the jokes told in a more vulgarity-tolerant society. Can also be used in its adjective form, yucky.

see also: blech, ew, yucky, ick, icky
Yuck-yuck, you make me laugh with your silly antics sometimes, Bob.

Yuck! There's a freakin' fly in my soup!
yuck by papermachete December 28, 2005
i. The phrase "yuck it up" was a way of mimicking laughter in '60s theatrical jargon. It was also used to describe the sound of laughing at comedy shows.

ii. A decade later, yuck became an expression of distaste or disgust, maybe due to the vulgarity of the jokes in the aforementioned comedy clubs.

Note: can also be used in adjective form, i.e., yucky

See also blech, ick, icky, ack, yech, blech, blah, bleh, yucky, hyuck & ew
i. Get ready to yuck it up, folks, it's Dan Ahdoot!

ii. Mr Wilson: Yuck! Who put this dead fly and clear, whitish fluid in my goddamn soup?! Dennnnis!!
yuck by Juwanna Tinkle October 29, 2005
Used as a synonym to denote something "nasty" / something ridiculously nice.
Taken from Kanye West feat. Pusha T & Ghostface - New God Flow:

I came aboard for more than just to rhyme with him
Think ’99, when Puff woulda had Shyne with him
YUCK
Matching Daytonas, rose gold on us
Goin' H·A·M in Ibiza done took a toll on us
Yuck by RBK79 December 5, 2012
An accomplice or partner who aids in getting an older person (50+) to partake in narcotics.
Yo, that yuck right there is trying to get my grandma to smoke some weed.
Yuck by Charles Golay August 27, 2017
Derogatory term for a white person; or proper term for a racist white person.

Normally I don't fight fire with fire but I found this one to cut reasonably deep.
Boy what be's you think you's doing up in this here seat?
--Can it Yuck.
Yuck by Ten Point Plan April 17, 2006