When you really need to take a piss, in reference to Sam O'nella's Swiss miss video where he called it:
" Swiss Miss, Instant Piss" in regards to the taste of only one packet.
When a guy is with 2 girls and he gets no action, but the girls hook up with each other. Like Switzerland, the guy remains neutral and misses an opportunityto be with 2 girls.
Last night, I watched 2 girls hook up and I was a swiss miss. We were all hanging out and next thing I know, they're hooking up and I got swiss missed.