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Literally, XD, but written as how it is pronounced in Spanish ("equis" for X, "de" for D).

Some use it as a toned down variant (similar to the ending a sentence with "lol" instead of "XD"). Nowadays, some use to distance themselves from old-school meme speak that overused the emoticon (such as "xdxdxdxd" in memes from communities like SDLG). Some use it more in ironic shiposts. However, tbh, most normal people use "equisde" and "XD" indistinctly.
Person 1: *posts 8/10 meme*
Person 2 (autistic, can't let go his childhood): "Pero qué wen momo la ptmr +10 lince :v"
Person 3 (autistic, zoomer): *replies with edgy XD image macro*
Person 4 (autistic, zoomer but younger and with ADHD): *replies with unrelated shitpost to farm likes*
Person 5 (average enjoyer of memes): "equisde"
equisde by 445731 June 12, 2022
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The pure incarnation of stupidity and bruh
That’s an equisde moment right there.
Equisde by TheClapGod October 14, 2019
Related Words

equisense 

two things making equal amounts of sense, decision wise.

like "six of one...."
it makes equisense to do option (a) or option (b)
equisense by amber January 30, 2005

Equisexy 

Being the same amount of sexy as another person.
That boy isn't that cute. I need someone equisexy to me or im not dating them.
Equisexy by ensexlopedia July 4, 2012

Equisential

1. Two events/items/objects/people of equal importance.
An amalgamation of 'equal' and 'essential'
Rob- "Are you going to the Cup Final or your friends wedding?"

John-"I cant decide at the moment, both are equisential to me!"
Equisential by Bangsyno1 April 13, 2010

equisket 

Guaranteed batshit crazy - A female who surrounds herself around the equine industry. Most often a trust fun baby. Can seduce with the flash of an American express card. Couldn’t ride one side of a bus and gets piped by old rich guys for pony’s and equestrian apparel.
Let’s go to the pub and find some new equiskets
equisket by anonymous July 23, 2021

Equisequester 

To Ethicquivelate* Carbon emissions with Carbon sequestration.
TraNZplant or PLaN B - PLant a Native Biofuel strives to Equisequester Carbon from emissions with plant sequestration.
Equisequester by PartisanZ July 26, 2022