hoss Share definition Flag A person, usually female, with large thighs... basically a fat person. "Guy 1: Damnn did you see that hoss, she took up half the fucking hallway." "Man that bitch is a fucking hoss." hoss by dreblockdrock April 19, 2008 0 0 Get merch Get the hoss mug. Buy Now — $32.95 See more merch