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Po-Po stands for police. Originated in Portland, Oregon for the Portland Police.
Guy 1: "Man you hear about Greg?"

Guy 2: "Nah man what happened?"

Guy 1: "The Po-Po caught him stealing."

Guy 2: "Man, The Po-Po know everything."
Po-Po by Andrew, T August 24, 2007
The five- 0..aka. the COPS
Holy SHARN here come the Po-Po's
Po-Po by KSchizzle * NCazazzle February 10, 2003
the police department
"The Po-Po caught Tony O'ing their car."
Po-Po by GoChicago February 10, 2006
A term, actually created by police officers, that stood for "Pissing off a Police Officer". How it came into modern day use is beyond me.
-Suspect spits on officers boot-
Officer: You honestly don't want to commit Po-Po today. Not today.
Suspect: Fuck you pig.
-Officer extends ASP baton and whacks suspect in the calf-
po-po by Sazanku February 26, 2007
Police. Good name to call them because they don't know what it means!!
'hey, what up, Po-Po'
Po-Po by Felixxxx September 27, 2005