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Gentleman's Trifecta 

Puking, pooping and ejaculating either simultaneously, or in sequence.
Woke up this morning after a long night of drinking. I had to complete the Gentleman's Trifecta, and now I'm late for work.

Birthday Trifecta 

Receiving a happy birthday text/call, tweet, and Facebook wall-post all from one person, on your birthday.
I thought I was more popular, but John was the only person who completed a Birthday Trifecta for me.

It's only 12:01 and I already completed Johns Birthday Trifecta.
Birthday Trifecta by iRod December 27, 2012

Trifecta 

An act whereby a man is able, in one night, to gain access to all three holes of a meretricious woman.

This can be summed easily into a wonderfully simplistic mnemonic: the yapper, the snapper, and the crapper.

Man, that chick is a fucking freak! I scored a trifecta on the first date with her.
Trifecta by chalmetteshocker December 16, 2008

Trifecta of Death

The combination of alcohol, benzodiazepines and heroin.
Scott died last night from the Trifecta of Death.
Trifecta of Death by Anty127 March 11, 2016

trifecta of smoking power 

When you smoke a cross joint and blow your fucking mind.
THATS, life.
This cross joint has a trifecta of smoking power.
trifecta of smoking power by N!C0 December 16, 2008

trifecta 

1. a horse-race betting combination wherein you pick three horses to win, place, and show. A difficult bet to win, with long odds and high returns.

2. Something President Bush said when a combination of three threats appeared and turned his popularity rating around in the 2001-2002 period.
trifecta by Figleaf23 January 2, 2009