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Although most commonly used to mean nigga or brother, alot of white kids use it to mean penis. It's actually a common slang for it in my area, So someone coudl be using it for that too.
"I am the ultimate nizzle" "dude.. do you have any idea what you just said?" "yes. I am the big penis" "... well then..."
nizzle by Melly November 12, 2004
Some to never be said by a white kid because you'll get your ass kicked.

The real meaning of "Fo shizzle my nizzle" is "for sure my nigga"
The real meaning of "Fo shizzle my nizzle" is "for sure my nigga"
nizzle by justin January 14, 2004
n. an African American; usually a male, but can refer to females
nizzle by Deev July 24, 2008
i need a joint
"i nizzle a jointizzle"

I Right 44 Zone On Two
I Rizzle 44 Zizzle On Tizzle

where my bitch
whizzle my bizzle

What What
Whizzle Whizzle

can yeah tell where white
nizzle by fo sheezy February 10, 2004
One's nose or one's nostril.
nizzle by Paul E Young May 6, 2006