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Monica Lewinsky Syndrome 

Also known as MLS. An act committed, so devastating that it single-handedly manages to become the definition of your character, no matter the greatness you had achieved up to that point or will achieve in the future.

Famous Victims:
Bill Clinton
R. Kelly
Tiger Woods
After Jeff punched that sorority chick in the face, his Monica Lewinsky Syndrome diminished his friend count both in RL and on facebook. All this occurred despite his ability to acquire "mad" kegs.

Randy's MLS left him forever: "the guy whole stole all that money from the church collections." Devaluing all the great work he had done up to this point.
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Monica Lewinsky 

Your mom is such a Monica Lewinsky!
Monica Lewinsky by ogrish_1982 April 25, 2006

Monica Lewinsky 

Yo bitch, come on over here and give me a 'ML'. A Monica Lewinsky.

Hannukah Lewinsky 

Eight Days in a Row of Blowjobs
Slick Willie probably got several batches of Hannukah Lewinskys
Hannukah Lewinsky by andy1 September 9, 2006

Monica Lewinsky 

"i did not have a sexual relationship with miss monica lewinsky"
Monica Lewinsky by finby December 18, 2005

Monica Lewinsky 

Monica Lewinsky got a mean head game dawg.
Monica Lewinsky by Jewish Drunkard September 27, 2006

Monica Lewinsky 

In golf, " a Lewinsky"
"Monica Lewinsky"
This is when putting to the cup, the ball runs around the edge of the cup and does not go into the hole.
A "Monica Lewsinsky" all lip and no hole
Or simply a "Lewinsky"
Monica Lewinsky by Swansea-jackacer September 16, 2009