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Short term for

"Piss me off"

Basically, when something slightly irritates you want somewhat exaggerate.
My god! The professor gave us 20 pages of homework. That totally ruined my weekend. PMO.

or

That neckbeard in front of us isn't wearing any deodorant. That "PMO."
PMO by percyclevland May 5, 2014
Related Words
"You bet $1000 on the game?!?!"
"Fuck yea I did boi. PMO!!
PMO by RandyMagnum2 September 17, 2018
Post #Metoo Obesity.
Hollywood woman who got fat after #metoo because men are not allowed to comment anymore.
That bitch PMO-ed after 2018
PMO by Kingkeezy May 20, 2020
Power moves only”, often used as an incentive for someone to shoot their shot, similar to YOLO
Friend 1: yooo Jessica’s so hot but I don’t think I’m gonna even try getting with her

Friend 2: bro c’mon it’s 2018!! PMO BABY!!
PMO by Dickdickdickdick2 January 20, 2018
pastor moji olagbegi
did you hear what pmo was saying in church last week?!
pmo by americannburnaboy September 1, 2022
Acronym for "poor me organ".

"that little voice, that twinge of doubt in your chest is your pmo. And that son of a bitch is a liar everyday, even if its one small step, you work towards ripping that son of a bitch out and throwing it to the lions. EVERYDAY, no excuses, never quit. Once you beat your PMO, you're unstoppable. More guys flunk ranger school from mental stress than physical. Discipline and drive is above muscles every day. Doesn't matter if you feel tired, sick, sad, it's your PMO. You say "fuck you" and finish the mission. Period." - a wise buddy of mine.
that little voice, that twinge of doubt in your chest is your pmo. And that son of a bitch is a liar
PMO by xDark_Alleyx01 January 30, 2019