sqwedgie Share definition Flag when a guy sweats in the scrotum area and his underwear gets stuck between the scrotum and the legs and must be picked to relieve the awful stuffy feeling. when pat ran a mile, he had a terrible sqwedgie and needed to pick it. sqwedgie by mooshkla June 9, 2005 0 0 Get merch Get the sqwedgie mug. Buy Now — $32.95 See more merch