Qwert is a substitution for the word fuck, or can be used to describe someone as a whore, so they are Qwerty, or are a Qwert. It has endless meanings and can be thrown into almost any sentence.
"Qwert off asshole."
"She really is a qwert isn't she..."
"Go qwert yourself."
Qwert Witness: GOSH! Wade's being such a qwert!
Person 2: What's he doing?
Qwert Witness: He's just complaining about how his life is so boring. taking it out on me
Person 2: Sucks for you