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To get your ass kicked REALLY badly. If you got "duffed", you didn't just get punched in the face, hit the floor and kicked once or twice hard... you got hit in the face, hit the ground, then got hit in the face several more times, possibly had your head bashed into the cement, got kicked in the ears, neck, kidneys and various other soft spots on your body.
"Yung, that nigga D-Set laid up in the hospital. He smoked up that whole QP he was fronted by main man and got duffed."
Duffed by Krill Awareness April 15, 2006

chickenskin dufflebag 

chickenskin dufflebag by JohnnyGuy December 19, 2007

Duffed It 

Referring to when you royally screw something up. Sometimes when you miss an easy shot in a sport.
Oh he duffed it!
Duffed It by Doo Doo Delpra June 28, 2011
The action of pounding a person's ass to the point their cheeks turn red without slapping them.
Yo man I duffed that bitch so hard her cotton picking grandma felt it dog.
Duffed by Mcduffing April 10, 2019

duffle bagging

stuffing your unerect penis into a condom and throwing it into a vagina
Tiffany: ...it feels loose, are you duffle bagging?

Near: yea, well deal with it.

Duffle Bag 

The act of stuffing a semi erect penis into a vagina.
Jay: "How could you fuck a chick that is that ugly?"

Ian: "I know! I couldn't get my dick hard enough so I had to duffle bag it in there!"
Duffle Bag by Jeff Mainland December 20, 2008