yezzir Share definition Flag Pharrells line, meaning "yes sir". Usually said very fast. (From the song "Can I Have it Like That") Ladies and gentlemen, Yezzir! Let's do it!, Yezzir! yezzir by Maggey Lafoxy January 5, 2007 0 0 Get merch Get the yezzir mug. Buy Now — $32.95 See more merch