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The general feeling of lethargy and well-being experienced after eating a satisfying meal. This phenomena is particularly triggered by foods high in carbohydrates and meats containing the amino acid tryptophan.
I got the itis so bad after the Thanksgiving meal I just chilled on the couch and watched some movies.
the Itis by Dorjan Scott February 16, 2004
When you become sleepy after eating food or getting some booty.
"Man after I ate that chinese food the Itis whupped my ass."
the Itis by Pistalwhipped.net January 27, 2004
When you call in sick to work but aren't really sick
"I think I'm going to catch the itis on Friday "
The itis by Quality associate March 2, 2014
a sexualy transmitted infection.
yo son dont stick yo dick up in that trick, she got the itis son, word is bond.
the itis by BALL$ June 23, 2007
When you're in a public space (such as a mall) and you gotta go. You feel trapped and you gotta get out of that store.
I have the Itis, I have to get out of this store right now before I go crazy
The Itis by edawg444 January 10, 2025

stick-in-the-mud-itis 

Typical of college students in long-distance relationships, it is the tendency to want to stay in on weekends with one's significant other rather than going out and enjoying time with friends.
Guy 1: Hey, you want to come out with us tonight? We're going to do crazy college things!
Guy 2: No, I have a lot of work to do...
Guy 1: Bull, that's just an excuse to chat with Suzy. Since when did you come down with stick-in-the-mud-itis?