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Informal nickname for a really fun, cool, authentic, funny, and laid back sister and/or closest friend.
Dude, me and my closest sissel were totally talking about that the other day!
Related Words
Sissel is a human, but barely. Sissels tend to be mean spirited and hypocritical.

If you ever meet a Sissel, you should run as fast as possible in the other direction.

Watch out for Sissel.
Ugh, that girl is such a bitch!

Bitch is an understatement, that's a Sissel!
Sissel by ChickenNuggetNoodle January 14, 2019
We have received a Sissel out of this inheritance...
Sissel by anonymous August 1, 2022

Sosselini 

Other word for cocaïne
We really need some sosselini tonight
Sosselini by vonnstone May 12, 2023

sissle bint 

A new term of endearment within the Drag community, especially in Australia. Combination of sissle which is a corruption of "sis" or "sister" and bint which means both "little girl" and "whore". Sissle bint doesn't carry the negative connotation of calling someone a whore, nor does it mean "little sister". It is just a friendly way to address a fellow drag queen or drag ally / enthusiast.
"Hey sissle bint, how was the drag show? Did you get lots of cash?"
"Don't talk to me, we aren't friends once we are off the stage, remember that."
"Relax, queen!"
sissle bint by Nathan Fogs November 20, 2015
The shy girl that you see but don't really notice. If you get under her layers of protection you will find a cute, sexy, open, warm and funny little girl that is hard to live without.
I never thougt she would be anything for me but she is such a Sisse.
Sisse by Nickusa2311 February 6, 2010