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to shoot, or empty a clip from your weapon (gun)
AW DAM, they let off shots Son!
let off by n'Vain August 22, 2008
Polite way your parents might enquire or announce if you've farted
Oh dear, father, I think Jeremy's let off again, open a window.
let off by David from Kingsbury November 4, 2003
Terminology for someone implying sexual favors implicitly, yet explicitly without directly stating it.
P1: I need a favor
P2: You know what you can do to speed things up. I'll see what I can do for you. Come by tonight.
P1: you mean let off?
Let Off by RG2301 April 13, 2017

Let off steam 

Get rid of one´s anger in a way that does not harm anyone
Running after work really helps me let off steam. I always feel better afterwards.
Let off steam by LostAcapulco November 8, 2009

let off in me 

To ejaculate inside a woman. Another way of asking someone to cum inside you.
Oh yeah baby, let off in me and watch it drip out..
let off in me by CreampieGuy25 December 17, 2017

let Fluffy off the leash 

Walking away from the group, he thought it was safe to let Fluffy off the leash.