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A handsome individual who rejected his humanity and in turn got all the hot babes.
Brian: I know you want to be a Keefe, but that's only a dream. Sometimes you just got to let some dreams go.
Kevin: Shut up Brian, you're just jealous that I'm getting closer to becoming a Keefe.
Keefe by CornyRonnie February 19, 2021
Related Words
The crystals that fall off really good marijuana.
After I shook that hydro, I had about a gram of killer keefe
keefe by Pilaf May 29, 2008
Gaelic meaning handsome, noble, gentle, lovable.
"Ach! You're so Keefe, I could just pinch your cheeks: both sets!"
Keefe by Elan J February 4, 2010
The most potent form of marijuana; marijuana that contains crystals.
keefe by Judah May 13, 2005
A very hot guy from Keeper of the Lost Cities who has perfect hair and is perfect for Sophie. Team Foster-Keefe all the way!
"Keefe is really fucking hot."

"You did NOT just insult the hair." -Keefe himself.
Keefe by Queen011CatFury February 10, 2023
My reason for living. Thank the gods for Shannon Messenger and her amazing mind.
I am madly in love with keefe science, who is a fictional character.
Keefe by Mossy_moss_moss March 15, 2022