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London / Cockney word used as a personal insult or put a person in his or her place.
I don't take no shit, especially off a nuffin' like you...
nuffin' by DJ Wechat April 5, 2017
"That's what I thought, them niggas was bluffin
They talk all day but say, nuffin" - DMX
nuffin by Jre May 23, 2003
person 1: hey, what's up?
person 2: nuffin..
person 1: *gives muffin*
nuffin by JDHAdrummer[DF] March 8, 2009
What you get when you're finished with a muffin; the absence of a muffin
Jeff: Hey, got any muffins?
Shan: Nope, I got nuffin
Nuffin by Dark Stom November 16, 2009
George is NUFFIN!

<Stu> "How bigs your package George?"
<George> "I've got NUFFIN. I am NUFFIN. Me, NUFFIN, same same."
Nuffin by Stu October 15, 2003
Not a muffin

The origin of this word of known to come from the deep south upwards to mid Virginia
I don't want nuffin
Nuffin by Umm_a_name November 9, 2021