by reptiles October 04, 2002
Get the X mug.by reptiles October 04, 2002
Get the scum-sucking pig dog mug.As a rule of thumb, it is profoundly unwise to take crack-cocaine. The brain has evolved a truly vicious set of negative feedback mechanisms. Their functional effect is to stop us from being truly happy for long. Nature is cruelly parsimonious with pleasure. The initial short-lived euphoria of a reinforcer as powerful as crack will be followed by a "crash". This involves anxiety, depression, irritability, extreme fatigue and possibly paranoia. Physical health may deteriorate. An intense craving for more cocaine develops. In heavy users, stereotyped compulsive and repetitive patterns of behaviour may occur. So may tactile hallucinations of insects crawling underneath the skin ("formication"). Severe depressive conditions may follow; agitated delirium; and also a syndrome sometimes known as toxic paranoid psychosis. The neural aftereffects of chronic cocaine use include changes in monoamine metabolites and uptake transporters. There is down-regulation of dopamine D2 receptors to compensate for their drug-induced overstimulation. Thus the brain's capacity to experience pleasure is diminished.
He was a normal guy until he started smoking crack, now he is a hustler that sucks dick for $5 to buy another rock.
by reptiles October 04, 2002
Get the crack mug.1. n. generally refers to the fruiting bodies of the fungus in the genus psilocybe. 2. any non-poisonous mushroom with visionary or entheogenic properties.
by reptiles October 04, 2002
Get the magic mushroom mug.by reptiles October 04, 2002
Get the dudes mug.by reptiles October 04, 2002
Get the SAUSAGE PARTY mug.by reptiles October 04, 2002
Get the goober mug.