1. To wrap a person or pet with
something fluffy so that
that person or pet becomes a giant fluffy object.
Originates from Mr. Fluff from Kirby's Epic Yarn
video game for the Wii. In that game, when Mr. Fluff or Kirby touches a snowball, he ends up being stuck inside of a giant rolling snowball. Thus, before a person picks up and throws his/her partner into a snowball to cause that partner to become a giant snowball, he/she must shout: "I will flufflez you!"
2. A soft edible food (such as ice cream or whip cream) that you put on other food (usually a waffle).