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a derogatory term used universally with all races.
can be used as zyker (ZkY3)as plural or to just be offenive.

guy1: hey that guy headshotedme, u damn zike!
guy2:wat, why call him a zyke?
guy1: cuz the d-bag won't tell me if he's black or asian!
by N of n0V3mber March 12, 2008
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2
A slur against male thots.
He was kissing a whole lot of boys last night, he's definitely a zyke
by furry militia September 30, 2018
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3
Zyke- A dirty or used q-tip that has been shoved in Donald trumps asshole.
Wow he looks like a zyke. He must be a dirty q-tip
by Toe-sucker April 20, 2018
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