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John Wayne It 

After having unprotected sex, the woman is left full of semen and as such has to do a John Wayne type walk to the bathroom to clean up, trying not to get cum running down her legs.
After we had sex, I had to John Wayne It to the bathroom real quick incase we woke his Dad up!
John Wayne It by Melanie M September 22, 2005

doing it john wayne style

Doing anal sex raw with no lube by accidentally slipping in and you just keep going at that point.
Joseph are you doing it John Wayne style.

Yes sorry I should just keep going.

Wayned It 

Where you mess up so incredibly hard that even your audience notices your mistake before you do.
Person 1: Hey have you seen how that youtuber WayneRadioTV messed up on saying a word on stream?
Person 2: Yeah. He Wayned It.
Wayned It by Inkie Devla :) October 12, 2023

lil waynes in it

when a song on your ipod comes on and your friends make fun of you for how gay it is and you say lil waynes in it to make it sound cool and get them to stop then change the song
in the car:
britney spears song comes on
hahaha fag
bro lil waynes in it
oh alright nvm then