A slur used towards transgender and transsexual people, usally transwomen but can also be used towards transmen.
"Hey did you hear, apparently sarah is a tranny!"
"You cant say that! Sarah goes by jake now and is transgender."
by Syke (Koda) July 31, 2017
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Refers to trans people. If it’s a cisgender person using it, it’s a slur. Tranny (when used as a slur) usually refers to women. It’s been kind of reclaimed so some trans people refer to themselves as tranny.
TERF: He’s pretending to be a she. Fucking tranny.

Person: be quiet now please
by anarchism_is_sexy June 21, 2020
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A very offensive slur to transgender people.
Guy 1: Hey look at that ugly tranny over there! Guy 2: May be the ugliest tranny I've ever seen.
by MessedUpSoul February 14, 2017
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A popular term for someone suffering from "gender dysmorphia," meaning unhappiness with one's gender. Such individuals long to be of the other gender, often suffer extreme angst due to their biological gender, and will often go to extraordinary lengths to live and outwardly appear as the gender they wish to be, including extensive chemical, surgical and prosthetic alterations of their bodies.

M2F is often used to refer to boys/men who think of themselves as female. F2M for girls/women who think of themselves as male.
1. Pablo got tricked by a tranny last weekend. He picked up one from the club thinking he was gonna get sum pussy, instead he got a chick with a dick.

2. You ever seen a porno with that actor Buck Angel? Yo, she looks like a straight-up, buffed, hardcore biker ex-con til she takes her boxers off and you see that its a woman with a big-ass juicy pussy! She looks like a real man but be taking all kinda dick just like a real woman. That shit blew my mind when I first say it.
by BxMuscle October 4, 2010
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In this day and age, it is commonly used by closed-minded bigots as a derogatory slur towards trans people.
by Your_Gay_Aunt March 14, 2019
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A derogative term used to describe transgender people. It is a slur.
Op friend: Look at that trannie over there!
Op: dude don’t say that, it’s transphobic.
by coolpersonwhoplaysvideogames November 20, 2020
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A person who wishes they were Transgender.
"I find FTM's so hot, sometimes I wish I was one!"
"Whatever...Tranny-be!"

"Jeffery Star is such a Tranny-be"
by Backwardsboy April 3, 2009
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