When a person, usually famous is streaming a multiplayer video game and a person in the audience tries to get into the same game that the streamer is in and targets them, or tries to somehow talk to them.

The real reason ninja switched to mixer

When ninja has so much ego that he can’t comprehend anyone being better than him.

This is usually used when someone watches your/someone elses stream to get an advantage, or they try to get into their game to kill them.
They usually land on top of you (fortnite) or find your base.
It fucking sucks.