shit of brain Share definition Flag when there is really shit in someone's brain , you can call him "hey , there is shit in your brain! " Hey Charly , there is really bunch of shit in your brain , you are really shit of brain now! shit of brain by Urban dictionary is litttttt November 19, 2017 0 0 Get merch Get the shit of brain mug. Buy Now — $32.95 See more merch