Someone who -- although often interesting -- is difficult to get along with on an every day basis. They often make simple things overly complex, or argue points ad infinitum.
Can you drive by my house this evening on your way to work?

Sure, I'll drive by. Do you want me to stop and pick you up when I'm driving by?

Of course I do. You're a real piece of work, aren't you?
by anon#E#moose September 25, 2006
Get the piece of work mug.
Unaware of one's foolishness. Originates from "What a Piece of Work is Man" monologue from Hamlet. More precisely an ironic reflection of how little most men achieve despite being endowed with relatively enormous powers to act and reason. Generally used as a sarcastic "compliment."
My boss can't operate the photocopier without the assistance of half the admin staff. He's a real piece of work!
by werdnurd June 2, 2009
Get the piece of work mug.
You had sex with the new girl?
"Ya butt she wasn't very good. I had to teach her what to do. Kinda like your wife, haha."
You really are a piece of work.
by Zenagin September 5, 2015
Get the piece of work mug.
Clean version of "piece of sh.." where overt profanity is out of place. Commonly refers to an individual who despite a wealth of help and "understanding", options yields utter disappointment. To accept one is naive.(Avoid) To reject one is to understand.(Recommend)
a real piece of work jerk wasteoid welfare ex loss rathole money pit useless hard to help incongruent
by RITZ January 16, 2017
Get the piece of work mug.
A person whose stupidity and ignorance never fail to amaze you.
dad: how could you end up with a $10,000 credit card bill?
me: let me think, I go to strip clubs every night...
dad: (shaking his head) you're a real piece of work.
by greekmonkey March 10, 2005
Get the piece of work mug.
a person who is both crazed and bizarre, yet charming at the same time
When my friend calls Shakespeare a hack trying to look like a good writer, I call her a piece of work
by carpenglishpurple9h May 7, 2011
Get the piece of work mug.
I'm not sure what it means. My boss says it all the time.

1) He says it about attractive women.

2) He says it about a retarded guy wearing a neon yellow reflective vest and riding a tricycle on the sidewalk.
1) Wooo, look at her. She's a piece of work.

2) Look at that guy. He's a piece of work isn't he?
by Lemminwinks May 23, 2007
Get the piece of work mug.