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An itch located deep within the anal cavity. One runs the risk of their appendage smelling like fecal matter if (s)he so chooses to take it on.
Example 1

Don: Why are you walking so funny?
Craig: Dude, I got a pickaxe!

Example 2

Don: Dude, you picking a wedgie?
Craig: No I just have a major pickaxe!

Example 3

Craig: Dude, smell my finger!
Don: Why?
Craig: I just took care of a pickaxe!
by fartmaster69 October 26, 2011
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2
A sexual position used by people with mighty long noses. When taking the girls pants off and before licking her out, insert thumb up her anal cavity and then using the nose as a penetrative tool, by moving the head back and forth into the vagina in a pick axe action
Rupert - "How are you feeling after our pick axeing last night??"
Megan - "A bit sore this morning, how's your pecker?"
Rupert - "I think i've broken my mighty long nose darling, serious pick axeing last night"
by J Samsone February 17, 2014
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3
adjective or interjection: alternate pronunciation of kickass, something that is extraordinarily sublime. Very cool.
Guy1: "Dude, did you see that pick axe hottie that I left the party with last night?"

Guy2: "Yeah, did you get some?"

Guy1: "Dude."

Guy2: "Pick axe."
by macazootie January 26, 2008
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4
Where during fellatio, the female giving said fellatio, purposefully jams her incisor tooth into the male's dick-hole, causing extreme pain or death and in some very rare cases, mild pleasure.
Bob was really enjoying Kim's blowjob, until she decided to Pickaxe him as revenge for giving her The Shocker earlier that evening.
by The Prariedogs January 12, 2010
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5
The grotesque and egregious act of placing your palm onto your shoulder to make the shape of a large bludgeon and then shoving it in ones anal cavity till they either die or are completely unfixable by any surgery.
After John got done beating Chris in basketball he began to pickaxe him while the other players held him down.
by Relyk2 May 24, 2018
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