Pick six 

A term used in football when a player of the defensive team intercepts the ball thrown by the quarterback of the offensive team and runs it back into the end zone for a 6 point touchdown. "Pick" is open to interpretation but is basically used for when the defensive player grabs the ball. The "six" is used to describe the six points earned from the touchdown.

"Did you see Kyle's pick six last night? It helped us win the game!"

Pick six by Brit Morgan October 22, 2013

PICK SIX 

AMERICAN FOOTBALL: An interception returned for a touchdown.

SPORTS FAN 1:"Did you see Ed Reeds' PICK SIX off Tom Brady last week?"

Sports Fan 2:"Hell yeah!The Ravens'season is over.Might as well play spoiler."

PICK SIX by L.MARTIN November 17, 2005

PICK SIX 

An interception returned for a touchdown in football. Basically what Aqib Talib would do every season when he’s done with Michael Crabtree’s chain.

Fan 1: Dude did you see Aqib Talib against the Raiders?
Fan 2: Oh yeah, Crabtree probably has to spend a lot of racks on a new chain.
Fan 1: No, I mean that nasty pick six.

PICK SIX by Maffs January 29, 2018

pick six 

cock blocking another dude and then scoring with the broad they were trying to hook up with

McNamara's about to pick six! Nick brought Nancy home but when Mc told her that Nick has the hiv, she suddenly wanted a little Irish in her.

pick six by The Dankl March 24, 2008

Pick Six 

Pick Six: having sex with six hot girls(that have boyfriends). it is also football terminolgy

Dude i just had a Pick Six. that was some was some awsome sex

Pick Six by exthboxth November 6, 2010